Actin filament dynamics impacts keratinocyte stem cell maintenance
نویسندگان
چکیده
منابع مشابه
Actin filament dynamics impacts keratinocyte stem cell maintenance
Cultured human epidermal keratinocyte stem cells (holoclones) are crucial for regenerative medicine for burns and genetic disorders. In serial culture, holoclones progressively lose their proliferative capacity to become transient amplifying cells with limited growth (paraclones), a phenomenon termed clonal conversion. Although it negatively impacts the culture lifespan and the success of cell ...
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ژورنال
عنوان ژورنال: EMBO Molecular Medicine
سال: 2013
ISSN: 1757-4676,1757-4684
DOI: 10.1002/emmm.201201839